Ion channels catalyze ionic permeation across membranes via water-filled pores.To understand how changes in intracellular magnesium concentration regulate the influx of Mg2+ into cells, we examine early events in the relaxation of Mg2+ channel CorA toward its open Gift Cards state using massively-repeated molecular dynamics simulations conducted ei
Is It Necessary Managing Carnivores to Reverse the Decline of Endangered Prey Species? Insights from a Removal Experiment of Mesocarnivores to Benefit Demographic Parameters of the Pyrenean Capercaillie.
Mesopredator control has long been used to alleviate the effect of elevated predation pressure on vulnerable, threatened or valuable species.However, the convenience of using mesopredator controls is technically questionable and scientifically-sound research is therefore required to evaluate the impact of predation on prey case by case.In this stud
Machine learning-based diagnostic prediction of minimal change disease: model development study
Abstract B12 METHYL Minimal change disease (MCD) is a common cause of nephrotic syndrome.Due to its rapid progression, early detection is essential; however, definitive diagnosis requires invasive kidney biopsy.This study aims to develop non-invasive predictive models for diagnosing MCD by machine learning.We retrospectively collected data on demog
Conflict Potential of Free-Roaming Horse Grazing on Timor Deer (Rusa timorensis Blainville 1822) Habitat in Torong Padang Cape Area, East Nusa Tenggara
Livestock grazing had been believed to affect on the existence of wildlife, including the timor deer (Rusa timorensis Blainville 1822) through competition.This study aimed to determine whether the free-roaming horse grazing owned by local communities in Torong Padang Cape, East Nusa Tenggara become a competitor for timor deer.Field observations and